Anatomy & Physiology of Pain

  • Nociceptors and sensory transduction
  • Spinal cord processing and The Gate Control Theory
  • Brain networks involved in pain (pain matrix)
  • Ascending and descending modulation
  • Central and peripheral sensitization
  • Neuroplasticity and chronic pain
  • Neuroimmune interactions (glia and cytokines)
  • Key brain regions involved in pain (insula, ACC, PFC, thalamus, PAG, etc.)
  • Placebo & Nocebo Mechanisms

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