Epidemiology and burden of pain

Pain is one of the most common health problems worldwide, and it occurs in two main forms: acute and chronic pain.
Acute pain comes on suddenly—often after an injury, surgery, or infection—and almost everyone experiences it at some point. It is one of the leading reasons for emergency department visits and short-term work absence. Studies suggest that up to 70% of surgical patients report moderate to severe acute postoperative pain, and poorly controlled acute pain can increase the risk of transitioning to chronic pain.

Chronic pain, defined as pain lasting longer than three months, is far more widespread than many people realize. Global estimates show that 20–30% of adults live with chronic pain, and about 10% experience severe, disabling pain that limits daily activities. Low back pain is consistently the number one cause of years lived with disability worldwide. Conditions such as osteoarthritis, neuropathic pain, and chronic headaches also contribute substantially to the overall burden.

The impact of pain—acute and chronic—extends well beyond physical symptoms. Chronic pain is linked with higher rates of depression and anxiety, reduced quality of life, and increased healthcare use. Economically, pain-related conditions account for hundreds of billions in direct and indirect costs each year in many high-income countries, due to medical expenses, lost productivity, and long-term disability.

As populations age and chronic health conditions become more common, the prevalence and societal impact of chronic pain are expected to grow. Improving awareness, prevention, early treatment of acute pain, and long-term support for chronic pain can help reduce this burden and improve quality of life for millions of people.

Economic Burden
  • Pain is one of the leading reasons for healthcare visits.
  • Costs arise from medical appointments, medications, procedures, and hospital stays.
  • In high-income countries, pain-related conditions cost hundreds of billions annually through:
    • Lost productivity
    • Sick leave
    • Long-term disability claims
Why It Matters

Effective prevention, early treatment, and long-term support can reduce the burden of pain.
Under-treated acute pain increases the risk of chronic pain.
Chronic pain is expected to rise due to ageing populations and longer life expectancy.

Chronic Pain Worldwide

References

1. Goldberg DS, McGee SJ. Pain as a global public health priority. BMC Public Health. 2011 Oct 6;11:770. doi: 10.1186/1471-2458-11-770. PMID: 21978149
2. Mills SEE, Nicolson KP, Smith BH. Chronic pain: a review of its epidemiology and associated factors in population-based studies. Br J Anaesth. 2019 Aug;123(2):e273-e283. doi: 10.1016/j.bja.2019.03.023. 2019 May 10
3. Rometsch, Carolinea,*; Martin, Alexandrab; Junne, Florianc; Cosci, Fiammettad,e. Chronic pain in European adult populations: a systematic review of prevalence and associated clinical features. PAIN 166(4):p 719-731, April 2025

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